Modulation of Alveolar Macrophage Activity by Eugenol Attenuates Cigarette-Smoke-Induced Acute Lung Injury in Mice

• Main Authors: Maria Clara Barbosa- (Author), Paolo Oliveira-Melo (Author), Marcos Henrique Gonçalves da Silva (Author), Flávio Santos da Silva (Author), Felipe Andrade Carvalho da Silva (Author), Bruno Vinicios Silva de Araujo (Author), Moacir Franco de Oliveira (Author), Aristides Tadeu Correia (Author), Sidnei Miyoshi Sakamoto (Author), Samuel Santos Valença (Author), Manuella Lanzetti (Author), Martina Schmidt (Author), Emanuel Kennedy-Feitosa (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigates the role of eugenol (EUG) on CS-induced acute lung injury (ALI) and how this compound is able to modulate macrophage activity. C57BL/6 mice were exposed to 12 cigarettes/day/5days and treated 15 min/day/5days with EUG. Rat alveolar macrophages (RAMs) were exposed to CSE (5%)...