Madagascine induces vasodilatation via activation of AMPK

• Main Authors: Dapeng Chen (Author), Bochao Lv (Author), Sei Kobayashi (Author), Yongjian Xiong (Author), Yuan Lin (Author), Salvatore Genovese (Author), Francesco Epifano (Author), Shanshan Hou (Author), Yunyan Ji (Author), Fusheng Tang (Author), Dandan Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Madagascine (3-isopentenyloxyemodin) can be chemically synthesized or purified from several Rhamnus species, and it is found to have more potent biological activities than the parent compound emodin. The aim of this study is to characterize the vasodilatory effect of madagascine on vasoconstriction...