Simple Meets Single: The Application of CRISPR/Cas9 in Haploid Embryonic Stem Cells
The CRISPR/Cas9 system provides a powerful method for the genetic manipulation of the mammalian genome, allowing knockout of individual genes as well as the generation of genome-wide knockout cell libraries for genetic screening. However, the diploid status of most mammalian cells restricts the appl...
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Format: | Book |
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Hindawi Limited,
2017-01-01T00:00:00Z.
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A1234.567 |
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