Development of In Situ Gelling Meloxicam-Human Serum Albumin Nanoparticle Formulation for Nose-to-Brain Application

• Principais autores: Gábor Katona (Autor), Bence Sipos (Autor), Mária Budai-Szűcs (Autor), György Tibor Balogh (Autor), Szilvia Veszelka (Autor), Ilona Gróf (Autor), Mária A. Deli (Autor), Balázs Volk (Autor), Piroska Szabó-Révész (Autor), Ildikó Csóka (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2021-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The aim of this study was to develop an intranasal in situ thermo-gelling meloxicam-human serum albumin (MEL-HSA) nanoparticulate formulation applying poloxamer 407 (P407), which can be administered in liquid state into the nostril, and to increase the resistance of the formulation against mucocilia...