Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration

• Main Authors: Paul Tamburini (Author), Dennis Vestergaard Pedersen (Author), Denise Devore (Author), Josh Cone (Author), Rekha Patel (Author), Todd Hunter (Author), Fang Sun (Author), Gregers Rom Andersen (Author), Jeffrey Hunter (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The bispecific antibody tarperprumig (ALXN1820) was developed as a treatment option for diseases involving dysregulated complement alternative pathway (AP) activity that could be administered in small volumes, either subcutaneously or intravenously. Tarperprumig incorporates a C-terminal variable do...