Effects of schistosomiasis on susceptibility to HIV-1 infection and HIV-1 viral load at HIV-1 seroconversion: A nested case-control study.

• Main Authors: Jennifer A Downs (Author), Kathryn M Dupnik (Author), Govert J van Dam (Author), Mark Urassa (Author), Peter Lutonja (Author), Dieuwke Kornelis (Author), Claudia J de Dood (Author), Pytsje Hoekstra (Author), Chifundo Kanjala (Author), Raphael Isingo (Author), Robert N Peck (Author), Myung Hee Lee (Author), Paul L A M Corstjens (Author), Jim Todd (Author), John M Changalucha (Author), Warren D Johnson (Author), Daniel W Fitzgerald (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomiasis affects 218 million people worldwide, with most infections in Africa. Prevalence studies suggest that people with chronic schistosomiasis may have higher risk of HIV-1 acquisition and impaired ability to control HIV-1 replication once infected. We hypothesized that: (1) pre-existing...