Phenotypic and functional profile of IFN-α-differentiated dendritic cells (IFN-DCs) from HIV-infected individuals

• Main Authors: Bruna Tereso Santillo (Author), Denise da Silva Reis (Author), Laís Teodoro da Silva (Author), Nathalia Teixeira Romani (Author), Alberto José da Silva Duarte (Author), Telma Miyuki Oshiro (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dendritic cell (DC)-based immunotherapy is a promising strategy for the treatment of HIV-infected individuals. Different from the conventional protocol for DC differentiation based on the cytokine IL-4 (IL4-DCs), several studies have suggested obtaining DCs by culturing monocytes with type I IFN (IF...