The Utilization of RNA Silencing Technology to Mitigate the Voriconazole Resistance of Aspergillus Flavus; Lipofectamine-Based Delivery

• Main Authors: Sanam Nami (Author), Behzad Baradaran (Author), Behzad Mansoori (Author), Parivash Kordbacheh (Author), Sasan Rezaie (Author), Mehraban Falahati (Author), Leila Mohamed Khosroshahi (Author), Mahin Safara (Author), Farideh Zaini (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Introducing the effect of RNAi in fungi to downregulate essential genes has made it a powerful tool to investigate gene function, with potential strategies for novel disease treatments. Thus, this study is an endeavor to delve into the silencing potentials of siRNA on cyp51A and MDR1 in vor...