Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis

• Автори: Qian Chen (Автор), Sijian Wang (Автор), Ruixia Bao (Автор), Dan Wang (Автор), Yuzheng Wu (Автор), Yi Zhang (Автор), Mengyang Liu (Автор), Tao Wang (Автор)
• Формат: Книга
• Опубліковано: BMC, 2024-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background The synthetic liver X receptor ligand (LXR) T0901317 (T0) has been reported to attenuate atherosclerosis (AS) without hyperglyceridemia due to innovative drug combination or nano-sized drug delivery. Given the key roles of mangiferin (MGF) in lipid metabolism and atherogenesis, i...