Calenduloside E Analogues Protecting H9c2 Cardiomyocytes Against H2O2-Induced Apoptosis: Design, Synthesis and Biological Evaluation

• Main Authors: Yu Tian (Author), Yu-Yang Du (Author), Hai Shang (Author), Min Wang (Author), Zhong-Hao Sun (Author), Bao-Qi Wang (Author), Di Deng (Author), Shan Wang (Author), Xu-Dong Xu (Author), Gui-Bo Sun (Author), Xiao-Bo Sun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Modulation of apoptosis is therapeutically effective in cardiomyocytes damage. Calenduloside E (CE), a naturally occurring triterpenoid saponin, is a potent anti-apoptotic agent. However, little is known about its synthetic analogues on the protective effects in apoptosis of cardiomyocytes. The pres...