Microbiological, Clinical, and PK/PD Features of the New Anti-Gram-Negative Antibiotics: β-Lactam/β-Lactamase Inhibitors in Combination and Cefiderocol-An All-Inclusive Guide for Clinicians

• Main Authors: Luigi Principe (Author), Tommaso Lupia (Author), Lilia Andriani (Author), Floriana Campanile (Author), Davide Carcione (Author), Silvia Corcione (Author), Francesco Giuseppe De Rosa (Author), Roberto Luzzati (Author), Giacomo Stroffolini (Author), Marina Steyde (Author), Giuliana Decorti (Author), Stefano Di Bella (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bacterial resistance mechanisms are continuously and rapidly evolving. This is particularly true for Gram-negative bacteria. Over the last decade, the strategy to develop new β-lactam/β-lactamase inhibitors (BLs/BLIs) combinations has paid off and results from phase 3 and real-world studies are beco...