QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation

• Päätekijät: Kentaro Ando (Tekijä), Toshiyasu Hombo (Tekijä), Akihiro Kanno (Tekijä), Hironobu Ikeda (Tekijä), Masakazu Imaizumi (Tekijä), Noritsugu Shimizu (Tekijä), Kengo Sakamoto (Tekijä), Shin-ichi Kitani (Tekijä), Yoshinori Yamamoto (Tekijä), Shingo Hizume (Tekijä), Keiko Nakai (Tekijä), Tetsuya Kitayama (Tekijä), Keiji Yamamoto (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2005-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious monkeys. As part of QT Interval Prolongation: Project...