Systematic druggable genome‐wide Mendelian randomization identifies therapeutic targets for sarcopenia

• Autors principals: Kang‐Fu Yin (Autor), Ting Chen (Autor), Xiao‐Jing Gu (Autor), Wei‐Ming Su (Autor), Zheng Jiang (Autor), Si‐Jia Lu (Autor), Bei Cao (Autor), Li‐Yi Chi (Autor), Xia Gao (Autor), Yong‐Ping Chen (Autor)
• Format: Llibre
• Publicat: Wiley, 2024-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background There are no effective pharmacological treatments for sarcopenia. We aim to identify potential therapeutic targets for sarcopenia by integrating various publicly available datasets. Methods We integrated druggable genome data, cis‐eQTL/cis‐pQTL from human blood and skeletal muscl...