Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3

Voltage-gated potassium channels (KVs) perform vital physiological functions and are targets in different disorders ranging from ataxia and arrhythmia to autoimmune diseases. An important issue is the search for and production of selective ligands of these channels. Peptide toxins found in scorpion...

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Main Authors: Andrei M. Gigolaev (Author), Alexey I. Kuzmenkov (Author), Steve Peigneur (Author), Valentin M. Tabakmakher (Author), Ernesto L. Pinheiro-Junior (Author), Anton O. Chugunov (Author), Roman G. Efremov (Author), Jan Tytgat (Author), Alexander A. Vassilevski (Author)
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Publicado em: Frontiers Media S.A., 2020-07-01T00:00:00Z.
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