Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway

• मुख्य लेखकों: Dian Xiong (लेखक), Fei Gao (लेखक), Jingbo Shao (लेखक), Yueyun Pan (लेखक), Song Wang (लेखक), Dong Wei (लेखक), Shugao Ye (लेखक), Yuan Chen (लेखक), Rui Chen (लेखक), Bingqing Yue (लेखक), Juan Li (लेखक), Jingyu Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Idiopathic pulmonary fibrosis is a severe and deadly form of diffuse parenchymal lung disease and treatment options are few. Alveolar epithelial type 2 (AEC2) cell senescence is implicated in the pathogenies of IPF. A major bioactive compound from the traditional Chinese medicine Fructus...