Artesunate, an Anti-Malaria Agent, Attenuates Experimental Osteoarthritis by Inhibiting Bone Resorption and CD31hiEmcnhi Vessel Formation in Subchondral Bone

• Main Authors: Yicheng Li (Author), Wenbo Mu (Author), Boyong Xu (Author), Jiangdong Ren (Author), Tuerhongjiang Wahafu (Author), Shalitanati Wuermanbieke (Author), Hairong Ma (Author), Hongwei Gao (Author), Yang Liu (Author), Keyuan Zhang (Author), Abdusami Amat (Author), Li Cao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a common and debilitating joint disease worldwide without interventions available to reverse its progression. Artesunate (ART), an anti-malaria agent, possesses diverse biological activities, including the inhibition of osteoclastogenesis and angiogenesis in various cells, but...