Genetic and Non-genetic Factors Contributing to the Significant Variation in the Plasma Trough Concentration-to-Dose Ratio of Valproic Acid in Children With Epilepsy

• Main Authors: Ze-Yue Xu (Author), Hong-Li Guo (Author), Ling Li (Author), Min Zhang (Author), Xia Jing (Author), Ze-Jun Xu (Author), Jin-Chun Qiu (Author), Xiao-Peng Lu (Author), Xuan-Sheng Ding (Author), Feng Chen (Author), Jing Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study was conducted to evaluate the potential genetic and non-genetic factors contributing to plasma trough concentration-to-dose (C0/D) ratio of valproic acid (VPA) in pediatric patients with epilepsy.Study Design: A single-center, retrospective cohort study was performed by collect...