Genetic and Non-genetic Factors Contributing to the Significant Variation in the Plasma Trough Concentration-to-Dose Ratio of Valproic Acid in Children With Epilepsy

• Egile Nagusiak: Ze-Yue Xu (Egilea), Hong-Li Guo (Egilea), Ling Li (Egilea), Min Zhang (Egilea), Xia Jing (Egilea), Ze-Jun Xu (Egilea), Jin-Chun Qiu (Egilea), Xiao-Peng Lu (Egilea), Xuan-Sheng Ding (Egilea), Feng Chen (Egilea), Jing Xu (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: This study was conducted to evaluate the potential genetic and non-genetic factors contributing to plasma trough concentration-to-dose (C0/D) ratio of valproic acid (VPA) in pediatric patients with epilepsy.Study Design: A single-center, retrospective cohort study was performed by collect...