The Potential of Cell-Penetrating Peptides for mRNA Delivery to Cancer Cells

• Auteurs principaux: Yelee Kim (Auteur), Hyosuk Kim (Auteur), Eun Hye Kim (Auteur), Hochung Jang (Auteur), Yeongji Jang (Auteur), Sung-Gil Chi (Auteur), Yoosoo Yang (Auteur), Sun Hwa Kim (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

In vitro transcribed mRNA for the synthesis of any given protein has shown great potential in cancer gene therapy, especially in cancer vaccines for immunotherapy. To overcome physiological barriers, such as rapid degradation by enzymatic attack and poor cellular uptake due to their large size and h...