Binase Immobilized on Halloysite Nanotubes Exerts Enhanced Cytotoxicity toward Human Colon Adenocarcinoma Cells

• Hlavní autoři: Vera Khodzhaeva (Autor), Anna Makeeva (Autor), Vera Ulyanova (Autor), Pavel Zelenikhin (Autor), Vladimir Evtugyn (Autor), Martin Hardt (Autor), Elvira Rozhina (Autor), Yuri Lvov (Autor), Rawil Fakhrullin (Autor), Olga Ilinskaya (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Many ribonucleases (RNases) are considered as promising tools for antitumor therapy because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus pumilus, triggers apoptotic response in cancer cells expressing RAS oncogene which is mutated in a large percentage of prev...