Phenformin Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice without Affecting Immune Cell Infiltration

• मुख्य लेखकों: Mikkel Ø. Nørgård (लेखक), Michael Christensen (लेखक), Henricus A.M. Mutsaers (लेखक), Rikke Nørregaard (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Phenformin and metformin are antihyperglycemic drugs that belong to the class of biguanides. Previously, we demonstrated that metformin elicits renoprotective effects in unilateral ureteral obstructed mice by reducing the infiltration of immune cells into the kidney. Since phenformin is a more poten...