Soluble Dipeptidyl Peptidase-4 Induces Fibroblast Activation Through Proteinase-Activated Receptor-2

• Main Authors: Shih-Yi Lee (Author), Shao-Tung Wu (Author), Yao-Jen Liang (Author), Ming-Jai Su (Author), Cheng-Wei Huang (Author), Yu-Hsuan Jao (Author), Hui-Chun Ku (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibroblasts are the chief secretory cells of the extracellular matrix (ECM) responsible for basal deposition and degradation of the ECM under normal conditions. During stress, fibroblasts undergo continuous activation, which is defined as the differentiation of fibroblasts into myofibroblasts, a cel...