Chromosome Segregation-1-like Gene Participates in Ferroptosis in Human Ovarian Granulosa Cells via Nucleocytoplasmic Transport

• Main Authors: Luanqian Hu (Author), Tongtong Hong (Author), Yuheng He (Author), Huiyuan Wang (Author), Jinxiang Cao (Author), Danhua Pu (Author), Li Gao (Author), Chao Gao (Author), Yugui Cui (Author), Jie Wu (Author), Rongrong Tan (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Premature ovarian insufficiency (POI) is defined as the depletion of ovarian function before the age of 40 years. The global prevalence of POI is 3.5%. To date, genetic factors account for 23.5% of the etiology of POI. Herein, a previously uncharacterized pathogenic homozygous variant of the chromos...