The frequency of POLE-mutation in endometrial carcinoma and prognostic implications: a systemic review and meta-analysis

• 主要な著者: Alaa Salah Jumaah (著者), Mais Muhammed Salim (著者), Hawraa Sahib Al-Haddad (著者), Katherine Ann McAllister (著者), Akeel Abed Yasseen (著者)
• フォーマット: 図書
• 出版事項: Korean Society of Pathologists & the Korean Society for Cytopathology, 2020-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background Endometrial carcinoma (EC) is classified into four distinct molecular subgroups including ultramutated DNA polymerase epsilon (POLE). POLE-mutated tumors have the best prognosis and are a promising target for immunotherapy. This meta-analysis consolidated the reported variation of POLE-mu...