Extracellular vesicles secreted by Giardia duodenalis regulate host cell innate immunity via TLR2 and NLRP3 inflammasome signaling pathways.

• Main Authors: Panpan Zhao (Author), Lili Cao (Author), Xiaocen Wang (Author), Jingquan Dong (Author), Nan Zhang (Author), Xin Li (Author), Jianhua Li (Author), Xichen Zhang (Author), Pengtao Gong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Giardia duodenalis, also known as G. intestinalis or G. lamblia, is the major cause of giardiasis leading to diarrheal disease with 280 million people infections annually worldwide. Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism participating in cells communications. The aim of...