Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani

A chromone-peptidyl hybrids series was synthesised and rationally repurposed towards identification of potential antileishmanial hits against visceral leishmaniasis. Three hybrids 7c, 7n, and 7h showed potential IC50 values (9.8, 10, and 12 µM, respectively) which were comparable to erufosine IC50 (...

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Main Authors: Ahmed H. E. Hassan (Author), Waleed A. Bayoumi (Author), Selwan M. El-Sayed (Author), Trong-Nhat Phan (Author), Yeon Ju Kim (Author), Chae Hyeon Lee (Author), Soo Bin Cho (Author), Taegeun Oh (Author), Gyeongpyo Ham (Author), Kazem Mahmoud (Author), Joo Hwan No (Author), Yong Sup Lee (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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