Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani

A chromone-peptidyl hybrids series was synthesised and rationally repurposed towards identification of potential antileishmanial hits against visceral leishmaniasis. Three hybrids 7c, 7n, and 7h showed potential IC50 values (9.8, 10, and 12 µM, respectively) which were comparable to erufosine IC50 (...

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ग्रंथसूची विवरण
मुख्य लेखकों: Ahmed H. E. Hassan (लेखक), Waleed A. Bayoumi (लेखक), Selwan M. El-Sayed (लेखक), Trong-Nhat Phan (लेखक), Yeon Ju Kim (लेखक), Chae Hyeon Lee (लेखक), Soo Bin Cho (लेखक), Taegeun Oh (लेखक), Gyeongpyo Ham (लेखक), Kazem Mahmoud (लेखक), Joo Hwan No (लेखक), Yong Sup Lee (लेखक)
स्वरूप: पुस्तक
प्रकाशित: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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