Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis

• Main Authors: Zeyuan Zhong (Author), Zhi Qian (Author), Xu Zhang (Author), Fancheng Chen (Author), Shuo Ni (Author), Zhanrong Kang (Author), Fangxue Zhang (Author), Dejian Li (Author), Baoqing Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Postmenopausal osteoporosis (PMOP) is a metabolic bone disease characterized by decreased bone density and strength due to the imbalance between osteogenesis and osteoclastogenesis. Postmenopausal estrogen withdrawal increases proinflammatory cytokines and increases the serum level of Receptor activ...