Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress

• Main Authors: Seo-Yoon Min (Author), Dong-Soo Ha (Author), Tae-Sun Ha (Author)
• פורמט: ספר
• יצא לאור: The Korean Society of Nephrology, 2018-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Background: Puromycin aminonucleoside (PAN) is a known podocytotoxin. PAN-induced nephrosis is a widely used animal model for studying human idiopathic nephrotic syndrome. Abnormal protein accumulation associated with podocyte-specific endoplasmic reticulum (ER) stress damages cells structurally and...