Resistance to cancer treatment: the role of somatic genetic events and the challenges for targeted therapies

• Main Authors: Gerald eBatist (Author), Jian Hui eWu (Author), Alan eSpatz (Author), Wilson H Miller (Author), Eftihia eCocolakis (Author), Caroline eRousseau (Author), Zuanel eDiaz (Author), Cristiano eFerrario (Author), Mark eBasik (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Therapeutic resistance remains a major cause of cancer-related deaths. Resistance can occur from the outset of treatment or as an acquired phenomenon after an initial clinical response. Therapeutic resistance is an almost universal phenomenon in the treatment of metastatic cancers. The advent of mol...