Synergistic Effect of Acetazolamide-(2-hydroxy)propyl β-Cyclodextrin in Timolol Liposomes for Decreasing and Prolonging Intraocular Pressure Levels

Synergistic Effect of Acetazolamide-(2-hydroxy)propyl β-Cyclodextrin in Timolol Liposomes for Decreasing and Prolonging Intraocular Pressure Levels

The purpose of this study was to design, for the first time, a co-loaded liposomal formulation (CLL) for treatment of glaucoma including timolol maleate (TM) in the lipid bilayer and acetazolamide (Acz)-(2-hydroxy)propyl β-cyclodextrin (HPβCD) complexes (AczHP) solubilized in the aqueous core of lip...

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Main Authors: Carmen M. Arroyo-García (Author), Daniela Quinteros (Author), Santiago D. Palma (Author), Cesáreo J. Jiménez de los Santos (Author), José R. Moyano (Author), Antonio M. Rabasco (Author), María Luisa González-Rodríguez (Author)
Format: Book
Published: MDPI AG, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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