Ester hydrolysis differentially reduces aconitine-induced anti-hypersensitivity and acute neurotoxicity: Involvement of spinal microglial dynorphin expression and implications for Aconitum processing

Aconitines, including bulleyaconitine A, probably the most bioactive and abundant alkaloids in Aconitum plant, are a group of diester C19-diterpenoid alkaloids with one acetylester group attached to C8 of the diterpenoid skeleton and one benzoylester group to C14. Hydrolysis of both groups is involv...

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Main Authors: Teng-Fei Li (Author), Yong-Xiang Wang (Author), Nian Gong (Author)
Format: Book
Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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