Triplet-Energy Quenching Functions of Antioxidant Molecules

• Main Authors: Carlos Angelé-Martínez (Author), Leticia Christina Pires Goncalves (Author), Sanjay Premi (Author), Felipe A. Augusto (Author), Meg A. Palmatier (Author), Saroj K. Amar (Author), Douglas E. Brash (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

UV-like DNA damage is created in the dark by chemiexcitation, in which UV-activated enzymes generate reactive oxygen and nitrogen species that create a dioxetane on melanin. Thermal cleavage creates an electronically excited triplet-state carbonyl whose high energy transfers to DNA. Screening natura...