Therapeutic applications of CRISPR/Cas9 mediated targeted gene editing in acute lymphoblastic leukemia: current perspectives, future challenges, and clinical implications

• Үндсэн зохиолчид: Alan Jhones Barbosa Assis (Зохиогч), Brunna Letícia de Oliveira Santana (Зохиогч), Ana Cristina Moura Gualberto (Зохиогч), Fabio Pittella-Silva (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Acute Lymphoblastic Leukemia (ALL) is the predominant hematological malignancy in pediatric populations, originating from B- or T-cell precursors within the bone marrow. The disease exhibits a high degree of heterogeneity, both at the molecular level and in terms of clinical presentation. A complex...