Pheophorbide A-Mediated Photodynamic Therapy Potentiates Checkpoint Blockade Therapy of Tumor with Low PD-L1 Expression

• Main Authors: Qinli Tong (Author), Jiaojiao Xu (Author), Aihua Wu (Author), Chen Zhang (Author), Afeng Yang (Author), Sihang Zhang (Author), Hongzheng Lin (Author), Wei Lu (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although the immune checkpoint blockade (ICB) has made a great success in cancer immunotherapy, the overall response rate to the ICB, such as anti-programmed death ligand 1 (PD-L1) therapy, remains only at 20-30%. One major reason is the low expression level of the immune checkpoint in a certain typ...