Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration

• Main Authors: Hugo Fernandes (Author), Alessandra Zonnari (Author), Ricardo Abreu (Author), Sezin Aday (Author), Marta Barão (Author), Inês Albino (Author), Miguel Lino (Author), Ana Branco (Author), Cátia Seabra (Author), Tânia Barata (Author), Ermelindo C. Leal (Author), José Guilherme Tralhão (Author), Lino Gonçalves (Author), Alwin de Jong (Author), Hendrika A.B. Peters (Author), Margreet R. de Vries (Author), Paula da Costa Martins (Author), Paul H.A. Quax (Author), Lino Ferreira (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial cell (EC) activity is essential for tissue regeneration in several (patho)physiological contexts. However, our capacity to deliver in vivo biomolecules capable of controlling EC fate is relatively limited. Here, we screened a library of microRNA (miR) mimics and identified 25 miRs capabl...