Pediatric Dosing of Ganciclovir and Valganciclovir: How Model‐Based Simulations Can Prevent Underexposure and Potential Treatment Failure

• मुख्य लेखकों: Karin Jorga (लेखक), Bruno Reigner (लेखक), Clarisse Chavanne (लेखक), Giuseppe Alvaro (लेखक), Nicolas Frey (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2019-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Intravenous ganciclovir and oral valganciclovir are effective in the prevention and treatment of pediatric cytomegalovirus (CMV) infection but various dosing regimens are used in medical practice. Population pharmacokinetic (PopPK) model‐based simulations were used to propose a new ganciclovir pedia...