MiR-145 is upregulated in the retarded preimplantation embryos and modulates cholesterol levels in mice preimplantation embryos through targeting Abca1

• Main Authors: Ou Jian (Author), Ni MengXia (Author), Xing Shiyu (Author), Meng QingXia (Author), Zou QinYan (Author), Ding Jie (Author), Wang Wei (Author), Wan Jiaojiao (Author), Li Hong (Author), Huang Yining (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Preimplantation embryonic lethality is a driver of female infertility. Certain microRNAs (miRNAs) have previously been demonstrated to play important roles in the regulation of embryogenesis. Methods Normally developing blastocysts and arrested embryos were collected from patient...