Protective Effect of Prostaglandin EP4-Receptor Agonist on Anti-glomerular Basement Membrane Antibody-Associated Nephritis

• Main Authors: Tadashi Nagamatsu (Author), Hirohito Imai (Author), Michiyo Yokoi (Author), Tsutomu Nishiyama (Author), Yasushi Hirasawa (Author), Toshiyuki Nagao (Author), Yoshio Suzuki (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prostaglandin E2-receptor subtypes, EP1, EP2, EP3, and EP4, are present in the kidney. The aim of this study was to elucidate the anti-nephritic effect of an EP4-receptor agonist on an experimental nephritic model. Mice were injected i.v. with anti-glomerulus antiserum to induce nephritis. Nephritic...