Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia-Reperfusion Injury in Mice

• Main Authors: Jin Sun (Author), Qing Yuan (Author), Lichen Guo (Author), Guangxu Xiao (Author), Tong Zhang (Author), Bing Liang (Author), Rongmei Yao (Author), Yan Zhu (Author), Yue Li (Author), Limin Hu (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stroke often results in neurological and neuropsychiatric sequela. Exosomes derived from brain endothelial cells (EC-Exo) protect neurons from hypoxic injury. However, the biological role of exosomes in apoptosis and synaptic plasticity remains unclear. This research aimed to assess whether cerebral...