The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313.

• Main Authors: Lizeth Lacharme-Lora (Author), Siân V Owen (Author), Richard Blundell (Author), Rocío Canals (Author), Nicolas Wenner (Author), Blanca Perez-Sepulveda (Author), Wai Yee Fong (Author), Rachel Gilroy (Author), Paul Wigley (Author), Jay C D Hinton (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over recent decades, Salmonella infection research has predominantly relied on murine infection models. However, in many cases the infection phenotypes of Salmonella pathovars in mice do not recapitulate human disease. For example, Salmonella Typhimurium ST313 is associated with enhanced invasive in...