A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT

• मुख्य लेखकों: Zhihao Fu (लेखक), Hongchuan Liu (लेखक), Lan Wang (लेखक), Chuanfei Yu (लेखक), Yalan Yang (लेखक), Meiqing Feng (लेखक), Junzhi Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

T cell immunoglobulin and ITIM domain (TIGIT) is a novel immune checkpoint that has been considered as a target in cancer immunotherapy. Current available bioassays for measuring the biological activity of therapeutic antibodies targeting TIGIT are restricted to mechanistic investigations because do...