A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT

T cell immunoglobulin and ITIM domain (TIGIT) is a novel immune checkpoint that has been considered as a target in cancer immunotherapy. Current available bioassays for measuring the biological activity of therapeutic antibodies targeting TIGIT are restricted to mechanistic investigations because do...

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Main Authors: Zhihao Fu (Author), Hongchuan Liu (Author), Lan Wang (Author), Chuanfei Yu (Author), Yalan Yang (Author), Meiqing Feng (Author), Junzhi Wang (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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