Pharmacokinetics and Pharmacodynamics of a Nanostructured Lipid Carrier Co-Encapsulating Artemether and miRNA for Mitigating Cerebral Malaria

• Main Authors: Veera Venkata Nishanth Goli (Author), Spandana Tatineni (Author), Umme Hani (Author), Mohammed Ghazwani (Author), Sirajunisa Talath (Author), Sathvik Belagodu Sridhar (Author), Yahya Alhamhoom (Author), Farhat Fatima (Author), Riyaz Ali M. Osmani (Author), Umamaheshwari Shivaswamy (Author), Vichitra Chandrasekaran (Author), Bannimath Gurupadayya (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerebral malaria (CM), a severe neurological pathology caused by <i>Plasmodium falciparum</i> infection, poses a significant global health threat and has a high mortality rate. Conventional therapeutics cannot cross the blood-brain barrier (BBB) efficiently. Therefore, finding effective...