Quercetin Alleviates Pulmonary Fibrosis in Mice Exposed to Silica by Inhibiting Macrophage Senescence

• Main Authors: Fei Geng (Author), Mengying Xu (Author), Lan Zhao (Author), Haoming Zhang (Author), Jiarui Li (Author), Fuyu Jin (Author), Yaqian Li (Author), Tian Li (Author), Xinyu Yang (Author), Shifeng Li (Author), Xuemin Gao (Author), Wenchen Cai (Author), Na Mao (Author), Ying Sun (Author), Heliang Liu (Author), Hong Xu (Author), Zhongqiu Wei (Author), Fang Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quercetin exerts anti-inflammatory, anti-oxidant and other protective effects. Previous studies have shown that senescent cells, such as fibroblasts and type II airway epithelial cells, are strongly implicated in the development of pulmonary fibrosis pathology. However, the role of senescent macroph...