Imipramine Administration in <i>Brucella abortus 2308</i>-Infected Mice Restores Hippocampal Serotonin Levels, Muscle Strength, and Mood, and Decreases Spleen CFU Count

• Main Authors: José Luis Maldonado-García (Author), Gilberto Pérez-Sánchez (Author), Enrique Becerril-Villanueva (Author), Samantha Alvarez-Herrera (Author), Lenin Pavón (Author), Luvia Sánchez-Torres (Author), Gabriel Gutiérrez-Ospina (Author), Manuel Iván Girón-Pérez (Author), Gabriela Damian-Morales (Author), Jesús Octavio Maldonado-Tapia (Author), Rubén López-Santiago (Author), Martha C. Moreno-Lafont (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brucellosis infection causes non-specific symptoms such as fever, chills, sweating, headaches, myalgia, arthralgia, anorexia, fatigue, and mood disorders. In mouse models, it has been associated with increased levels of IL-6, TNF-α, and IFN-γ, a decrease in serotonin and dopamine levels within the h...