Supplemental Insulin-Like Growth Factor-1 and Necrotizing Enterocolitis in Preterm Pigs

• Main Authors: Kristine Holgersen (Author), Xiaoyan Gao (Author), Rangaraj Narayanan (Author), Tripti Gaur (Author), Galen Carey (Author), Norman Barton (Author), Xiaoyu Pan (Author), Tik Muk (Author), Thomas Thymann (Author), Per Torp Sangild (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Recombinant human IGF-1/binding protein-3 (rhIGF-1/BP-3) is currently tested as a therapy in preterm infants but possible effects on the gut, including necrotizing enterocolitis (NEC), have not been tested. The aim of this study was to evaluate if rhIGF-1/BP-3 supplementation in the firs...