Risperidone Decreases Expression of Serotonin Receptor-2A (5-HT2A) and Serotonin Transporter (SERT) but Not Dopamine Receptors and Dopamine Transporter (DAT) in PBMCs from Patients with Schizophrenia

• Main Authors: Samantha Alvarez-Herrera (Author), Mauricio Rosel Vales (Author), Gilberto Pérez-Sánchez (Author), Enrique Becerril-Villanueva (Author), Yvonne Flores-Medina (Author), José Luis Maldonado-García (Author), Ricardo Saracco-Alvarez (Author), Raúl Escamilla (Author), Lenin Pavón (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dopamine and serotonin receptors and transporters play an essential role in the pathophysiology of schizophrenia; changes in their expression have been reported in neurons and leukocytes. Each antipsychotic induces a unique pattern in leukocyte function and phenotype. However, the use of polytherapy...