West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms.

• Main Authors: Elizabeth A Dietrich (Author), Stanley A Langevin (Author), Claire Y-H Huang (Author), Payal D Maharaj (Author), Mark J Delorey (Author), Richard A Bowen (Author), Richard M Kinney (Author), Aaron C Brault (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

West Nile virus (WNV) replicates in a wide variety of avian species, which serve as reservoir and amplification hosts. WNV strains isolated in North America, such as the prototype strain NY99, elicit a highly pathogenic response in certain avian species, notably American crows (AMCRs; Corvus brachyr...