Colistin Induces Oxidative Stress and Apoptotic Cell Death through the Activation of the AhR/CYP1A1 Pathway in PC12 Cells

• Autori principali: Baofu Xie (Autore), Yue Liu (Autore), Chunhong Chen (Autore), Tony Velkov (Autore), Shusheng Tang (Autore), Jianzhong Shen (Autore), Chongshan Dai (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2024-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Colistin is commonly regarded as the "last-resort" antibiotic for combating life-threatening infections caused by multidrug-resistant (MDR) gram-negative bacteria. Neurotoxicity is a potential adverse event associated with colistin application in clinical settings, yet the exact molecular...