Bystander Effects of Hypoxia-Activated Prodrugs: Agent-Based Modeling Using Three Dimensional Cell Cultures

Intra-tumor heterogeneity represents a major barrier to anti-cancer therapies. One strategy to minimize this limitation relies on bystander effects via diffusion of cytotoxins from targeted cells. Hypoxia-activated prodrugs (HAPs) have the potential to exploit hypoxia in this way, but robust methods...

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Bibliographic Details
Main Authors: Cho R. Hong (Author), Gib Bogle (Author), Jingli Wang (Author), Kashyap Patel (Author), Frederik B. Pruijn (Author), William R. Wilson (Author), Kevin O. Hicks (Author)
Format: Book
Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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