Cordycepin promotes browning of white adipose tissue through an AMP-activated protein kinase (AMPK)-dependent pathway

• Main Authors: Guihong Qi (Author), Yue Zhou (Author), Xiaopo Zhang (Author), Jiaqi Yu (Author), Xin Li (Author), Xiaoxue Cao (Author), Chongming Wu (Author), Peng Guo (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is a worldwide epidemic. Promoting browning of white adipose tissue (WAT) contributes to increased energy expenditure and hence counteracts obesity. Here we show that cordycepin (Cpn), a natural derivative of adenosine, increases energy expenditure, inhibits weight gain, improves metabolic p...