Evaluation of the bioequivalence of two formulations containing the combination of 400 mg of acetaminophen (paracetamol), 4 mg of phenylephrine and 4 mg of chlorpheniramine in capsules: open-label, three-way crossover study, partially replicated in healthy volunteers of both sexes

• Main Authors: Alessandra Ferreira dos Santos (Author), Quevellin Alves dos Santos (Author), Carlos Eduardo Melo Correa (Author), Edvaldo Capobiango Coelho (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was carried out in order to compare the relative bioavailability of two different formulations containing 400 mg of acetaminophen + 4 mg of phenylephrine hydrochloride + 4 mg of chlorpheniramine maleate, Test formulation (Cimegripe®) and Reference formulation (Resfenol®) in 84 healthy vol...